It was so exciting to find LDN medication for Ankylosing Spodylitis. When I found it, it took me about 2, 3 weeks to make my mind up to actually try to get the prescription because I was scared that it might be a false hope. I took it on the Thursday night – when I woke up in the morning I felt like I was never ill. I was straight (my posture), and the day before I was curled up, it was amazing! Anyone with AS should try it, you have got nothing to lose.